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5-(2-ethoxyethyl)-5-[4-(4-fluorophenoxy)phenoxy]pyrimidine-2,4,6(1H,3H,5H)-trione
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the diphenylether class and structurally related to barbituric acids. It acts as an inhibitor of matrix metalloproteinase 13 (MMP13), also known as collagenase 3. MMP13 is involved in the breakdown of extracellular matrix components and has been implicated in various pathological processes such as osteoarthritis and cancer metastasis. The drug has been studied primarily at the preclinical or experimental level for its potential to modulate MMP13 activity[1][6]. There are no approved indications or advanced clinical trials reported for this molecule.
- Other names
- 5-(2-ethoxyethyl)-5-[4-(4-fluorophenoxy)phenoxy]barbituric acid5-[4-(4-fluorophenoxy)phenoxy]pyrimidine-2,4,6(1H,3H,5H)-trione5-(2-ethoxyethyl)-5-[4-(4-fluorophenoxy)phenoxy]-1,3-diazinane-2,4,6-trione
02
Targets
MMP13 (Matrix metalloproteinase-13)
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